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甲状腺功能障碍和心血管疾病:使用大数据分析的关联研究.

Pedro Iglesias1,2, María Benavent3, Guillermo López3

  • 1Department of Endocrinology and Nutrition, University Hospital Puerta de Hierro Majadahonda, Instituto de Investigación Sanitaria Puerta de Hierro Segovia de Arana, Majadahonda, Madrid, Spain. piglo65@gmail.com.

Endocrine
|August 15, 2023
PubMed
概括
此摘要是机器生成的。

甲状腺功能障碍症显著增加患心血管疾病 (CVD) 和心血管风险因素 (CVRF) 的风险,无论年龄或性别. 这项研究强调了甲状腺功能过高和主要心血管并发症之间的强烈联系.

关键词:
心房动是一种心房动.糖尿病是一种糖尿病.脱脂血症是什么意思 脱脂血症是什么意思在高血压的高血压.甲状腺功能过强症 甲状腺功能过强症吸烟的习惯 吸烟的习惯

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科学领域:

  • 内分泌学和心脏病学.
  • 医疗保健中的大数据分析

背景情况:

  • 甲状腺激素对心血管 (CV) 系统有着深刻的影响.
  • 甲状腺功能低下症和甲状腺功能增强症都会增加严重心血管并发症的风险.

研究的目的:

  • 评估甲状腺功能障碍与主要心血管风险因素 (CVRFs) 和心血管疾病 (CVDs) 之间的关联.
  • 使用 Savana Manager 平台的大数据方法来进行全面的分析.

主要方法:

  • 观察性,回顾性研究设计.
  • 数据来源于西班牙Puerta de Hierro Majadahonda大学医院的电子医疗记录.
  • 采用人工智能和Savana Manager 3.0软件进行数据提取和分析.

主要成果:

  • 甲状腺功能障碍 (1.02%的540,939名患者) 与较高的CVRF和CVD频率有显著的关联 (p < 0.0001).
  • 在所有年龄和性别组的甲状腺功能过高患者中观察到升高的CVRF和CVD.
  • 栓塞性中风 (6.40) 和心房动 (5.99) 的概率比率最高;甲状腺功能增高与除栓塞性中风以外的大多数心血管疾病独立相关.

结论:

  • 在被研究的人群中,甲状腺功能过高,CVRFs和CVDs之间确实存在显著的关联.
  • 无论患者的年龄和性别,这些发现都是正确的.
  • 展示了人工智能在分析现实世界健康数据中的实用性.