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自发性崩作为人类芽细胞瘤的预后标志物:系统性审查和元分析

Kate Bickendorf¹, Fang Qi², Kelli Peirce¹

¹Fertility North, Joondalup, Western Australia, Australia.

Human reproduction (Oxford, England)

|August 15, 2023

概括

人类胚胎囊中的自发性崩 (SC) 与IVF中的更低的怀孕和euploidy率有关. 然而,SC并没有显著影响活产或流产率,这表明它会影响怀孕早期的结果.

科学领域:

生殖医学和胚胎学
在体外受精 (IVF)
胚胎发育和生存能力

背景情况:

人类胚胎囊细胞的自发崩 (SC) 是通过时间间隔监测观察到的现象,它对性和临床结果的影响尚不清楚.
现有的文献缺乏系统审查和元分析,以澄清SC在IVF中的预后价值.
了解SC作为胚胎活力的标志物的作用,对于提高试管婴儿成功率至关重要.

结论:

囊胞SC会对早期怀孕的结果产生负面影响,包括临床和持续怀孕率,以及胚胎平分化.
呈现SC的胚胎细胞应被认为是子宫内转移的较低优先级.
应将SC纳入预测试管婴儿成功的算法,以提高治疗效率.

关键词:

胚胎细胞囊中的胚胎囊.崩崩,崩崩,崩崩,崩崩,崩崩.合同是指一个合同的合同.扩张扩张扩张活生生的出生是活生生的出生.这是一个元分析.流产流产流产流产普洛伊迪 (Ploidy) 是一个平的人.收缩时间收缩时间时间延迟的时间延迟.

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Cleavage and Blastulation

Cleavage and Blastulation

After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.