马达加斯加艾滋病毒感染患者的粘膜皮肤表现:跨部门研究
Fandresena Arilala Sendrasoa1, Volatiana Mercia Falimiarintsoa1, Lala Soavina Ramarozatovo1
1Département de Dermatologie, Faculté de Médecine, Université d'Antananarivo, Antananarivo, Madagascar.
JMIR dermatology
|August 15, 2023
概括
粘膜皮肤表现在艾滋病毒患者中很常见. 口服候群病,梅毒和状腺炎与较低的CD4计数相关,这表明艾滋病毒感染个体的免疫状况.
科学领域:
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
背景情况:
- 超过90%的艾滋病毒感染患者经历了粘膜皮肤表现.
- 马达加斯加艾滋病毒患者皮肤病学发现的数据有限.
研究的目的:
- 评估马达加斯加艾滋病毒感染患者的粘膜皮肤表现的频谱.
- 确定这些表现和CD4细胞计数之间的关系.
主要方法:
- 从2013年1月到2020年3月进行了一项横截面研究.
- 包括328名18岁以上的HIV阳性患者,正在接受或正在等待抗逆转录病毒治疗.
主要成果:
- 167名患者 (51%) 至少有一次粘膜皮肤病变.
- 常见的表现包括口腔候群病,脂质性皮肤炎和卡波西肉瘤.
- 较低的CD4细胞计数与口腔候群病,梅毒和阴茎炎相关.
结论:
- 口腔候群病,梅毒和状腺炎可以表明艾滋病毒患者的免疫状况.
- 增加的皮肤表现与艾滋病毒的进展和免疫力下降相关.
相关概念视频
Immunodeficiency Diseases
974
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
974
Retrovirus Life Cycles
46.2K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
46.2K
Sexually Transmitted Infections
349
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
349


