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在患有哈希莫托甲状腺炎的妇女中,情绪性情和精神症状之间的关联
Gordana Stanić1,2, Snežana Marinković3, Jelena Milin Lazović4
1Academy of Applied Studies Belgrade Department of School of Applied Health Sciences, Belgrade, Serbia.
PloS one
|August 15, 2023
概括
与健康个体相比,哈西莫托的甲状腺炎患者表现出不同的情绪性情和更高的精神症状. 这些气质与症状水平有关,特别是在甲状腺功能低下病例中,这表明存在复杂的相互作用.
科学领域:
- 精神病学和内分泌学 精神病学和内分泌学
- 自免疫性疾病 自免疫性疾病
- 个性特征 个性特征
背景情况:
- 哈西莫托甲状腺炎 (HT) 是一种常见的自身免疫性甲状腺疾病,可能与情绪障碍有关.
- 情绪性气质 (AT),一种人格特征,与情绪障碍有关.
- 了解AT和HT中精神病症状之间的关系至关重要.
研究的目的:
- 研究新诊断出哈西莫托甲状腺炎 (HT) 的女性的主导情绪性情 (AT) 和精神症状之间的关联.
- 为了比较这些协会在妇女的HT (甲状腺下降和甲状腺下降) 与健康个体的对照组.
主要方法:
- 一个观察性横截面研究,嵌套病例控制设计.
- 146名参与者:73名女性患有HT (49名甲状腺功能低下,24名甲状腺功能良好) 和73名健康对照.
- 通过塞尔维亚的TEMPS-A评估AT和通过4DSQ评估精神症状.
主要成果:
- 超心动性AT在所有组中普遍存在.
- 与对照组相比,HT组显示了抑郁和循环动态AT的差异.
- 患有HT的女性报告了更高的痛苦和体化水平.
- 在甲状腺功能低下的HT中,所有AT方面与精神病体症状相关.
- 在euthyroid HT中,关联是特定于抑郁/循环动态AT和痛苦/体化.
结论:
- 在HT子组和对照组之间,在AT和精神病症状之间的关联中存在显著差异.
- 需要进一步研究更大的样本大小,以阐明这些复杂的关系在euthyroid和 hypothyroid HT.
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