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通过使用DMS探测进行pH差异性突变分析来表征RNA中的质子结合合体

Edgar M Faison, Amrita Nallathambi, Qi Zhang

    Journal of the American Chemical Society
    |August 15, 2023
    PubMed
    概括

    一种新的方法,pH差异性突变分析 (PD-MaP),可以大规模检测与质子化相关的RNA结构变化. 这项技术揭示了广泛的质子结合RNA组合,表明了广泛的生物作用.

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