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Updated: Jul 19, 2025

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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Published on: December 15, 2011

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LGI1脑炎和IgG4相关疾病:罕见疾病碰撞

Aaron Jesuthasan1, Tara Barwick2, Luke Dixon2

  • 1From the Charing Cross Hospital (A.J.); Department of Radiology (T.B.), Imperial College Healthcare NHS Trust, London, United Kingdom; Department of Surgery and Cancer (L.D.), Faculty of Medicine, Imperial College London, United Kingdom; London North West University Healthcare NHS Trust (S.M.); Department of Brain Sciences (M.R.J.), Faculty of Medicine, Imperial College London; and Renal Department (J.A.P.T.), Imperial College Healthcare NHS Trust, London, United Kingdom. aaronjesuthasan@gmail.com.

Neurology(R) neuroimmunology & neuroinflammation
|August 15, 2023
PubMed
概括

氨酸丰富的质瘤失活型1 (LGI1) 大脑炎和IgG4相关疾病 (IgG4RD) 可能有共同的潜在机制. 本案例报告强调了它们的同时发生和共享的治疗反应.

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Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
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