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Updated: Jul 19, 2025

In Vitro Analysis of E3 Ubiquitin Ligase Function
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装有MAVS的未定Lys63连接的多比基链激活了RIG-I-MAVS信号级联

Feng Liu1,2, Wanxin Zhuang1,2, Bin Song3

  • 1Key Laboratory of Infection and Immunity of Shandong Province & Key Laboratory for Experimental Teratology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, P.R. China.

Cellular & molecular immunology
|August 15, 2023
PubMed
概括

这项研究揭示了MAVS聚合物的未定K63结合的多基化如何调节RIG-I类受体信号传递. USP10二维基因酶和Ube2N-Riplet/TRIM31结合酶复合体控制这个过程,影响病毒防御.

关键词:
聚合是一种聚合.马夫斯 (MAVS) 是一种动物.在RIG-I中,RIG-I是指RIG-I.USP10 10美元的价格没有固的K63连接的多比基链.

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