现实世界的2型糖尿病发病率 美国的一个州的2型糖尿病缓解 保险人群使用大型行政索赔数据库
Natalie E Sheils1, Megan S Jarvis1, Lauren R Bangerter1
1Optum Labs, Minnetonka, MN.
概括
追溯索赔数据可以使用2021年共识定义来评估2型糖尿病缓解. 该方法允许对缓解率和相关因素进行人口层面的分析.
科学领域:
- 内分泌学 在内分泌学.
- 医疗信息学 医疗信息学
- 公共卫生 公共卫生
背景情况:
- 根据2021年共识声明,二型糖尿病缓解的定义是3个月停止降血糖治疗后A1C<6.5%.
- 在大量人群中使用行政索赔数据评估糖尿病缓解是具有挑战性的,因为数据有限.
研究的目的:
- 评估使用以实验室值为基础的回顾性索赔数据来评估2型糖尿病缓解的可行性.
- 确定不同缓解定义如何影响缓解流行率和队列特征.
- 为了确定有或没有足够数据用于缓解评估的队列之间的差异.
主要方法:
- 使用了商业保险和医疗保险优势会员的非身份化行政索赔数据,包括实验室值.
- 应用了2021年共识定义和三个替代标准 (血糖,时间,药理学) 来评估缓解灵敏度.
- 分析了524,076名2型糖尿病成年人的数据.
主要成果:
- 35.4%的个人缺乏足够的数据来评估缓解,尽管他们在初始A1C和地理位置上与评估者相似.
- 3.2%的被评估个人符合2021年2型糖尿病缓解的共识定义.
- 替代定义的缓解率从0.8%到2.3%;缓解队列更可能是女性,初始A1C较低和较高的减肥手术患病率.
结论:
- 实验室价值丰富的索赔数据使得2型糖尿病缓解的可行评估成为可能.
- 开发基于索赔的稳定缓解标志物可以促进人口层面的研究和结果评估.
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