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卡莱宾A向HIF-1α/NF-κB通路,以抑制结直肠癌细胞迁移

Aranka Brockmueller1, Sosmitha Girisa2, Mahzad Motallebi3

  • 1Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilians-University Munich, Munich, Germany.

Frontiers in pharmacology
|August 16, 2023
PubMed
概括

卡莱宾A (CA) 通过向缺氧诱导因子-1α (HIF-1α) 和NF-κB. 抑制结肠直肠癌 (CRC) 细胞迁移和增殖. 这种化合物通过调节瘤恶性瘤的关键因素,显示出癌症治疗的前景.

关键词:
3D阿尔基酸盐的使用方法在CRC迁移过程中,CRC的迁移卡勒宾是一个A.这就是HIF-1α.在 NF-κBB 中.灭症 (apoptosis) 是一种死亡的过程.新血管生成新血管生成瘤微环境是一个微环境.

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