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身体活动与疾病严重程度和疲劳有关,但与复发性缓解性多发性硬化症患者的复发率无关 - - 这是一项基于问卷的自我报告研究

Marit L Schlagheck¹, Sven T Hübner², Niklas Joisten¹

¹Division of Performance and Health, Institute for Sport and Sport Science, Technical University Dortmund, Dortmund, Germany.

Frontiers in neurology

|August 16, 2023

概括

身体活动可以减少多发性硬化症患者的疾病严重程度和疲劳. 然而,这项研究没有发现活动水平和复发率在复发性缓解多发性硬化症 (RRMS) 患者之间存在显著联系.

科学领域:

神经学神经学
康复医学康复医学康复医学
公共卫生公共卫生

背景情况:

多发性硬化症 (MS) 是一种慢性神经疾病,影响着全世界数以百万计的人.
理论上,身体活动可以改善多发性硬化症的症状,包括疲劳和疾病进展.
了解身体活动对复发性复发性多发性硬化症 (RRMS) 的具体影响对于患者管理至关重要.

研究的目的:

检查RRMS患者自我报告的体力活动与疾病严重程度之间的相关性.
调查RRMS患者体验的体力活动水平和疲劳之间的关系.
确定身体活动是否影响RRMS复发率.

主要方法:

在2019年3月至2021年8月期间,对253名被诊断患有RRMS的个人进行了调查.
使用戈丁休时间运动问卷 (GLTEQ) 评估身体活动.
疾病严重程度 (PDDS) 和疲劳 (FSMC) 用经过验证的天平进行测量,并记录复发率.

主要成果:

在体力活动水平和疾病严重程度 (PDDS,p<0.001) 之间观察到显著的逆相关性.
身体活动与疲劳水平也有显著的反向关系 (FSMC,p<0.001).
在体力活动水平与年度复发率 (p>0.05) 之间没有发现统计学意义上的关联.

结论:

在RRMS患者中,自我报告的体育活动与较低的疾病严重程度和疲劳有关.
身体活动似乎没有显著影响该人口的年度复发率.
这些发现支持将体育活动纳入RRMS的管理策略,重点是缓解症状.

关键词:

疾病的严重程度.疲劳疲劳疲劳疲劳疲劳疲劳多发性硬化症多发性硬化症身体活动身体活动复发缓解复发的多发性硬化症

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