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Updated: Jul 19, 2025

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一个保存的第二个球体残留在Lytic多糖单氧酶中的铜位反应性

Kelsi R Hall1, Chris Joseph2, Iván Ayuso-Fernández1

  • 1Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway.

Journal of the American Chemical Society
|August 16, 2023
PubMed
概括

在铜中心附近保存的谷氨酸/谷氨酸酸残留微调了酸多糖单氧酶 (LPMO) 功能. 突变影响酶的反应性,稳定性和催化机制,为LPMO活动和合成催化剂设计提供了洞察力.

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