英国的饮食障碍遗传学倡议
Dina Monssen1,2, Helena L Davies1, Saakshi Kakar1,2
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
The International journal of eating disorders
|August 16, 2023
概括
英国饮食障碍遗传学倡议 (EDGI UK) 是英国最大的饮食障碍研究,收集遗传和环境数据. 这项研究加快了对饮食障碍原因和并发症的理解.
科学领域:
- 饮食障碍中的遗传学和环境因素.
- 饮食障碍的精神和身体并发症.
- 英国人口中饮食障碍的流行病学.
背景情况:
- 饮食障碍是严重的心理健康状况,具有重大社会成本.
- 资金不足在历史上限制了饮食障碍研究.
- 英国饮食障碍遗传学倡议 (EDGI UK) 旨在解决这一研究缺口.
研究的目的:
- 描述EDGI英国的研究协议.
- 详细介绍最初的EDGI英国样本的人口统计,诊断和并发症.
- 建立EDGI英国作为加速饮食障碍研究的资源.
主要方法:
- 通过在线注册 (edgiuk.org) 招募16岁以上有终身饮食障碍诊断的参与者.
- 收集在线问卷数据,用于基因分析的唾液样本,以及同意医疗记录链接.
- 与国家卫生和护理研究院 (NIHR) 合作精神健康生物资源和饮食障碍慈善机构Beat.
主要成果:
- 截至2022年9月,招募了7435名参与者,57.8%的参与者返回了唾液DNA套件.
- 该样本主要是女性 (98%),白人 (93.1%), cisgender (97.8%) 和异性恋 (65.9%).
- 常见的诊断包括神经性厌食症 (48.3%),清洗障碍 (37.8%) 和神经性吃症 (37.5%).
结论:
- 英国EDGI是英国最大的饮食障碍研究,为研究提供了重要的资源.
- 正在进行的努力旨在增强研究样本的多样性.
- 这项研究促进了合作研究,以提高对饮食障碍及其并发性疾病的理解和治疗.
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