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Updated: Jul 19, 2025

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis
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miR-30e-5p通过Cyb561/ROS信号通路调节白血病干细胞的自我更新

Yanwen Ge1, Mei Hong1, Yu Zhang1

  • 1School of Life Sciences, Shanghai University, Shanghai, 200444.

Haematologica
|August 16, 2023
PubMed
概括

微RNA miR-30e-5p,在急性髓性白血病 (AML) 中经常降低,通过准Cyb561.1,抑制白血病干细胞 (LSC) 自再生. 这一发现为AML治疗提供了新的治疗策略.

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