在患有人类免疫缺陷病毒的患者中,Mopox感染后的亚急性甲状腺炎
Emmanuel Ssemmondo1, Mohamed Akasha Idris2, Damian Mawer3
1Academic Diabetes, Endocrinology & Metabolism, University of Hull, Hull, United Kingdom.
Endocrinology, diabetes & metabolism case reports
|August 16, 2023
概括
蒙博克斯 (以前是水) 感染可能导致亚急性甲状腺炎,这是一个罕见的内分泌并发症. 这一案例凸显了认识到这种情况及其有效使用类固醇治疗的重要性.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 在2022年,Mpox (以前的麻疹) 被宣布为全球卫生紧急情况.
- 亚急性甲状腺炎是一种甲状腺炎症状况.
- 蒙波克斯和亚急性甲状腺炎之间的关联以前没有在人类中被记录下来.
研究的目的:
- 报告在人类中Mpox感染后出现的第一个记录下来的亚急性甲状腺炎病例.
- 描述这种并发症的临床表现,诊断结果和治疗方法.
主要方法:
- 一份病例报告显示,一名51岁的男性患有人类免疫缺陷病毒 (HIV) 感染,在Mpox诊断后3周出现症状.
- 临床评估,实验室调查 (甲状腺功能测试,C反应蛋白,病毒PCR) 和成像 (胸部X射线图).
- 用抗甲状腺药物治疗,propranolol,随后使用普雷尼索隆.
主要成果:
- 患者出现了部不适,疲劳,体重减轻和夜间出汗.
- 血液测试显示C反应蛋白,自由T4和抑制TSH的升高,与负甲状腺抗体.
- 症状随着普雷迪尼索隆疗程迅速消失,随后是使用levothyroxine管理的甲状腺功能低下症的发展.
结论:
- 蒙博克斯病毒感染可以引起亚急性甲状腺炎,类似于其他病毒感染.
- 类固醇治疗在治疗Mpox相关的亚急性甲状腺炎方面是有效的.
- 临床医生应考虑Mpox患者出现相关症状的亚急性甲状腺炎,特别是排除其他感染后.
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