爱尔兰实习生紧急研究网络 (ITERN):五年的合作
James Foley1,2, Jeffrey Mulcaire3,4, Marcus Jee3,5
1Irish Trainee Emergency Research Network (ITERN), Dublin, Ireland. jamesfoley@rcsi.ie.
Irish journal of medical science
|August 16, 2023
概括
爱尔兰实习生紧急研究网络 (ITERN) 表明,实习生领导的协作对有影响力的紧急医学研究是可行的. 这些网络增强了个人和医疗机构的研究能力.
科学领域:
- 紧急医疗 紧急医疗
- 医疗教育 医学教育
- 医疗保健服务研究 医疗服务研究
背景情况:
- 应急医学的学员在发展研究能力方面经常面临挑战.
- 协作研究网络可以克服个人的局限性,促进更广泛的参与.
研究的目的:
- 描述爱尔兰实习生紧急研究网络 (ITERN) 的建立,成功和挑战.
- 突出在紧急医疗研究中由实习生领导的协作者的潜力.
主要方法:
- 这篇文章概述了ITERN的发展过程和运营策略.
- 它详细介绍了紧急医疗实习生采用的协作模式.
主要成果:
- 伊特恩已经证明了在紧急医疗领域由实习生领导的协作研究的可行性.
- 该网络促进了有影响力的研究项目,并增强了其成员的研究能力.
结论:
- 像ITERN这样的实习生领导的研究网络可以产生重要的以患者为中心的研究.
- 这种合作对于扩大医疗保健系统内的研究能力至关重要.
相关概念视频
01:45ER Retrieval Pathway
3.9K
In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...
3.9K
01:31Regulation of the Unfolded Protein Response
2.5K
Inositol-requiring kinase one or IRE1 is the most conserved eukaryotic unfolded protein response (UPR) receptor. It is a type I transmembrane protein kinase receptor with a distinctive site-specific RNase activity. As the binding mechanics of the misfolded proteins with the N-terminal domain of IRE-1 are unclear, three binding models — direct, indirect, and allosteric -- are proposed for receptor activation. Nevertheless, it is known that once a misfolded protein associates with IRE1, it...
2.5K