经常性尿路感染的管理:非抗生素捆绑治疗
Sergio Venturini1, Ingrid Reffo2, Manuela Avolio3
1Department of Infectious Diseases, ASFO Santa Maria degli Angeli Hospital of Pordenone, Pordenone, Italy.
Probiotics and antimicrobial proteins
|August 16, 2023
概括
一个新的多式联络护理包显著减少了76%以上的反复性尿路感染 (rUTIs) 和90%以上的抗生素使用. 这种方法也改善了参与者的生活质量.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 复发性尿路感染 (rUTIs) 很普遍,导致严重的发病率和影响生活质量.
- 鲁蒂对抗生素处方做出了重大贡献,加剧了人们对多药耐药生物 (MDRO) 的担忧.
- 现有的非抗生素策略提供了部分益处,但多式联络干预措施仍未得到充分探索.
研究的目的:
- 评估一种新型"护理包"在治疗复发性尿路感染方面的有效性.
- 评估多模式干预对感染复发,抗生素消耗,慢性症状和生活质量的影响.
主要方法:
- 一项前性研究在三年内招募了被诊断患有RUTI的女性.
- 参与者接受了为期六个月的"护理包",包括行为改变,益生菌 (口服和阴道),D-曼诺斯和蔓越.
- 对干预期前六个月和干预期后六个月的结果进行了比较.
主要成果:
- 观察到RUTIs显著减少76%和抗生素暴露减少90%以上 (p < 0.001).
- 报告了高坚持 (87.2%) 的护理包.
- 80.5%的参与者经历了生活质量的改善,慢性症状减少的趋势.
结论:
- 多模式的"护理包"有效地减少了RUTI的复发和抗菌药物的使用.
- 这种干预表明,它有可能改善女性的慢性症状和生活质量.
- 需要进一步的大规模研究来验证这些有希望的发现.
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