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Updated: Jul 19, 2025

A Semi-High-Throughput Adaptation of the NADH-Coupled ATPase Assay for Screening Small Molecule Inhibitors
10:28

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Published on: August 17, 2019

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氨酸三酸酸酶和脂肪酸合成抑制:一个叙事评论

Freddy Duarte Lau1, Robert P Giugliano2

  • 1Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas.

JAMA cardiology
|August 16, 2023
PubMed
概括

孟佩多酸是一种腺三酸酸酶 (ACLY) 抑制剂,有效降低了对他类药物不耐受患者的LDL-C. 清晰的结局试验显示了适度的心血管益处,并确定了潜在的副作用,如痛风.

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