脑源性神经营养因子血清水平与瘤的严重程度之间的关系
Putri Astrid Novianti Nazli1, Ariyati Yosi1, Khairina Nasution1
1Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Indonesia.
概括
这项研究发现,脑衍生神经营养因子 (BDNF) 水平和瘤严重程度之间没有显著的联系. 梅拉斯玛是什么意思
科学领域:
- 皮肤病学 皮肤病学
- 神经科学是一个神经科学.
- 生物化学 生物化学
背景情况:
- 黑色素是一种常见的超色素障碍.
- 大脑衍生神经营养因子 (BDNF) 在各种皮肤疾病中起作用.
- 需要进一步调查BDNF和瘤严重程度之间的关系.
研究的目的:
- 为了研究血清BDNF水平与乳腺瘤严重程度之间的相关性.
- 为了探索疹的潜在生物标志物.
主要方法:
- 这是一项涉及30名黑色素瘤患者的横截面研究.
- 测量了血清中的BDNF水平.
- 使用克鲁斯卡尔-瓦利斯测试评估了梅拉斯玛严重程度,并与BDNF水平相关联.
主要成果:
- 观察到BDNF水平与黑色素持续时间之间存在中度负相关性 (p=0.007).
- 没有发现BDNF水平与乳腺瘤严重程度之间有显著的关系 (p=0.387).
- 阳光暴露被确定为主要的风险因素.
结论:
- BDNF水平与瘤严重程度没有显著的关系.
- 梅拉斯马的发病是多因素的,涉及遗传学,荷尔蒙和环境因素,如阳光照射.
相关概念视频
02:17The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...