住宅绿地与人类微生物群之间的关联:来自多个国家的证据
Yi-Dan Zhang1, Shu-Jun Fan2,3, Zheng Zhang4
1Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Environmental health perspectives
|August 16, 2023
概括
更高的住宅绿色与皮肤和肠道样本中微生物丰富度的增加有关. 这项全球性研究表明,自然暴露与人类微生物群多样性之间存在联系,这可能会对健康产生影响.
科学领域:
- 环境健康 环境健康
- 微生物组研究的研究.
- 全球卫生健康 全球卫生健康
背景情况:
- 绿色或植被土地密度与健康有关,但其对人类微生物群的影响还未得到充分研究.
- 现有的证据因地区,样本大小和不确定的发现而受到限制.
研究的目的:
- 调查住宅绿色暴露与人类微生物多样性和组成之间的关联.
- 分析来自大型跨国样本 (34个国家) 的数据,以了解全球模式.
主要方法:
- 使用规范差异植被指数 (NDVI) 和增强植被指数 (EVI) 评估绿色.
- 采用线性回归用于α-多样性和变多变量方差分析 (PERMANOVA) 构成.
- 利用DESeq2进行微生物种群的差异丰度分析.
主要成果:
- 增加的绿色与手掌和肠道样本中较高的微生物丰富度相关.
- 肠道微生物群的均性随着绿色暴露的增加而下降.
- 特定的属,如 *Lactobacillus* 和 *Bifidobacterium* 较为丰富,而 *Anaerotruncus* 和 *Streptococcus* 较少,绿色较高.
结论:
- 住宅绿色与人类皮肤和肠道微生物的丰富性和组成有关,在全球不同的环境中.
- 研究结果表明,环境绿色和人类微生物群之间存在联系,这需要进一步调查健康结果.
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