诺塞博效应 (Nocebo效应) 是一种可怕的效应
1Department of Pain and Translational Symptom Science and Placebo Beyond Opinions Center, School of Nursing, University of Maryland, Baltimore, Maryland, USA;
Annual review of pharmacology and toxicology
|August 16, 2023
概括
负面的nocebo反应,与药物效应无关的负面结果,伤害患者并破坏治疗. 了解这些nocebo效应对于改善临床实践和研究至关重要.
科学领域:
- 神经科学是一个神经科学.
- 医学心理学 医学心理学
- 临床药理学 临床药理学
背景情况:
- 诺塞博反应是医疗治疗的不良结果,不能用药理学效应来解释.
- 这些负面影响,比安慰剂反应了解得更少,可能会伤害患者并影响治疗坚持.
- 触发因素包括口头建议,过去的负面经历和环境线索.
研究的目的:
- 审查nocebo效应和反应的多方面的方面.
- 探索在nocebo现象背后的不断积累的神经生物学机制.
- 讨论临床影响,伦理考虑和未来的研究方向.
主要方法:
- 关于nocebo效应研究的综合文献综述.
- 对神经生物学机制的研究进行分析.
- 综合与临床实践和试验相关的发现.
主要成果:
- 诺塞博效应受到心理因素和环境环境的影响.
- 神经生物学途径正在越来越多地被阐明.
- 显然对患者的治疗结果和治疗疗效有重大影响.
结论:
- 在临床环境和研究中,nocebo反应构成了重大挑战.
- 对神经生物学机制的进一步研究对于缓解策略至关重要.
- 解决nocebo效应对于患者的福祉和治疗成功至关重要.
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