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Updated: Jul 19, 2025

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
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跨膜螺旋之间的直接相互作用稳定了细胞P450 2B4和细胞B5氧化还原复合体

Bikash R Sahoo1, Ayyalusamy Ramamoorthy1

  • 1Biophysics Program, Department of Chemistry, Macromolecular Science and Engineering, Biomedical Engineering, Michigan Neuroscience Institute, The University of Michigan, Ann Arbor, MI 48109-1055, USA.

Biophysical chemistry
|August 16, 2023
PubMed
概括

细胞染色体P450 2B4 (CYP2B4) 和细胞染色体b5 (Cyt-b5) 在ER膜中形成一个复合体,由盐桥和疏水相互作用驱动. 这种复杂化增强了结构稳定性和结合亲和力,影响了药物代谢.

关键词:
细胞染色体P450的使用.细胞染色体-b5 的使用.脂质二层是什么意思氧复合物复合物是指氧复合物复合物.结构 结构 是一个结构.跨膜-跨膜的 跨膜

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