大麻使用障碍与青少年群体精神健康障碍之间的关联:一个队列研究
Regina Muñoz-Galán1, Irene Lana-Lander1, Marta Coronado1
1Public Health Agency of Catalonia, Department of Health, Government of Catalonia, Programme on Addictions, HIV, STI and Viral Hepatitis, Barcelona, Spain.
European addiction research
|August 16, 2023
概括
在加泰罗尼亚寻求治疗大麻使用障碍 (CUD) 的年轻人显示,患上精神健康障碍的风险明显更高. 这凸显了针对CUD青少年的有针对性的预防策略的迫切需要.
科学领域:
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
背景情况:
- 早期使用大麻和依赖使用模式与精神健康障碍有关.
- 有限的队列研究存在于患有大麻使用障碍 (CUD) 的青少年的心理健康发展.
研究的目的:
- 为了确定精神健康障碍的累积发病率.
- 评估在加泰罗尼亚 (2015-2019) 接受CUD治疗的未成年人中发展心理健康障碍的风险.
主要方法:
- 使用加泰罗尼亚卫生监督系统进行的回顾性固定队列研究.
- 暴露队列:为CUD治疗的未成年人 (n=948);配对队列:匹配的对照 (n=4,737).
- 排除先前有心理健康诊断的个人;使用条件Poisson模型估计的发病率比率.
主要成果:
- 精神健康障碍的累积发病率在CUD队列中为19.6%,在对照队列中为3.1%.
- 在CUD队列中,患精神疾病的风险增加了8.7倍.
- 与男性 (15.8%) 相比,女性的发病率较高 (32.7%);最常见的诊断包括严重的压力反应,适应障碍和人格障碍.
结论:
- 接受CUD治疗的青少年面临着明显增加患精神疾病的风险.
- 对CUD和相关心理健康状况的进一步研究对于制定有效的预防策略至关重要.
- 了解导致CUD发展的因素对于公共卫生干预至关重要.
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