在COVID-19后的患者中,与未感染者相比,执行功能障碍更大
Jacqueline H Becker1, Jenny J Lin1, Akosua Twumasi1
1Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA.
患有冠状病毒疾病-19 (COVID-19) 的患者更有可能经历执行功能障碍. 建议进行认知查,即使是那些患有轻度至中度COVID-19的人.
科学领域:
- 神经科学是一个神经科学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在冠状病毒疾病-19 (COVID-19) 后,患者经常报告认知障碍 (CI).
- COVID-19和CI发病率增加之间的关联需要进一步调查.
研究的目的:
- 评估COVID-19与认知障碍 (CI) 发生率之间的关联.
- 为了将COVID-19后患者的CI发病率与未感染的对照进行比较.
主要方法:
- 来自西奈山卫生系统COVID-19后登记册的数据分析.
- 包括417名COVID-19后患者和151名对照.
- 使用多个认知领域的验证措施进行CI评估.
- 后勤回归模型用于确定CI的赔率比率,以混因素进行调整.
主要成果:
- 与对照组相比,COVID-19后的患者在执行功能中表现出显著更高的CI概率 (OR:2.19).
- 在门诊 (OR:2.22) 和住院 (OR:3.59) 环境中观察到执行功能障碍的几率更高.
- 对于其他认知领域的CI,没有发现显著的关联.
结论:
- 后COVID-19患者表现出执行功能障碍的可能性增加.
- 对于患有轻度至中度COVID-19的个人,建议进行集中认知查.
- 需要进一步研究COVID-19后认知障碍的病理生理学和治疗方法.
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