同时的细菌内心炎与大血管封闭症的住院患者的情况更差有关
Ian A Ramsay1, Turki Elarjani2, Vaidya Govindarajan2
1MD-MPH Program, University of Miami Miller School of Medicine, Miami, Florida, USA ian.ramsay@med.miami.edu.
Journal of neurointerventional surgery
|August 16, 2023
概括
在细菌内心炎患者中,急性缺血性中风的机械血栓切除术显示,与仅有中风的患者相比,死亡率和并发症率更高. 需要进一步的研究,以改善这一脆弱人群的结果.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 干预性神经辐射学
背景情况:
- 细菌内心炎经常导致神经系统并发症,包括急性缺血性中风 (AIS).
- 机械血栓切除术 (MT) 对大血管封闭性 (LVO) 中风有效,但对其在内心炎患者的使用数据有限.
研究的目的:
- 评估机械血栓切除术对同时患有细菌性内心炎的患者的大血管封闭性中风的结果.
主要方法:
- 从2015年10月到2019年使用了国家住院样本 (NIS) 数据库.
- 鉴定了接受中脑动脉LVO的MT的患者.
- 使用多变量逻辑回归计算赔率比率.
主要成果:
- 与仅有57,420名AIS患者相比,接受MT的635名BE患者的AIS患者的死亡率显著更高 (26.8%vs10.2%),例行出院率更低 (10.2%vs20.9%).
- 患有BE的AIS患者死亡几率增加 (OR 3.94),例行出院几率降低 (OR 0.23),治疗后脑出血率更高 (39.4%对23.7%).
- 在BE患者的AIS中,观察到其他并发症的几率更高,如水头,呼吸衰竭,急性损伤和败血症.
结论:
- 机械血栓切除术是可行的内心炎患者LVO中风,但与更糟糕的临床结果相关.
- 需要进行进一步的研究,以阐明临床过程,并开发在内心炎患者中发生中风的改进治疗方法.
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