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Microfluidics in Assessing Platelet Function
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骨科手术患者血小板数下降后手术的特征,观察和见解.
George Zacharia1, Bartosz Walczyszyn1, Kolton Smith1
1Lenox Hill Hospital, New York, NY, USA.
Hematology, transfusion and cell therapy
|August 16, 2023
概括
手术后的骨科手术患者经常经历血小板数减少 (PLT),通常在第二天看到的最低水平. 然而,临床上显著的血小板缺血是罕见的,特别是在年轻的患者.
科学领域:
- 整形外科手术 整形外科手术
- 血液学 血液学 血液学
背景情况:
- 骨科手术后血小板数减少 (PLT) 是常见的.
- 手术后血小板缺血的特征仍未得到充分研究.
研究的目的:
- 描述骨科手术患者手术后血小板缺血的发生率和特征.
- 确定影响术后PLT减少的因素.
主要方法:
- 膝关节或关节置换患者 (2012-2015) 的回顾性图表审查.
- 排除接受肝素治疗的患者.
- 在手术后的0-4天对血小板数的分析.
主要成果:
- 90.9%的患者在手术后的第一天显示PLT减少.
- 最低的PLT发生在第2天 (平均201.3 × 10 ^ 9 / L),平均下降24%.
- 老年患者 (>65岁) 与年轻患者相比,PLT减少显著增加 (p=0.007).
结论:
- 在骨科手术中,即使没有肝素,术后的PLT减少也很常见.
- 临床显著的血小板缺血 (<100 × 10^9/L) 是不常见的.
- 老年患者需要更密切地监测手术后的PLT变化.
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