细丝性病原体作用者通过内细胞分裂进入植物细胞
Haixia Wang1, Ely Oliveira-Garcia2, Petra C Boevink3
1State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest Agriculture & Forestry University, Yangling, Shanxi 712100, China; Division of Plant Science, School of Life Sciences, University of Dundee, James Hutton Institute, Errol Road, Invergowrie, Dundee DD2 5DA, UK.
菌和菌菌病原体通过克拉特林介导内细胞分裂 (CME) 将效应蛋白送入植物细胞. 这项研究调查了病原体如何触发CME,并在宿主细胞内释放因子,以有效感染.
科学领域:
- 植物病理学 植物病理学
- 细胞生物学 细胞生物学
- 分子相互作用分子相互作用.
背景情况:
- 来自真菌和菌菌病原体的细胞质效应物被植物细胞内化.
- 克拉特林介导的内细胞分裂 (CME) 被确定为效应器进入的机制.
- 效应因子吸收和细胞内贩运的确切机制尚不清楚.
研究的目的:
- 探索效应体分泌途径在宿主细胞吸收中的作用.
- 为了阐明在病原体攻击后宿主细胞中CME的触发因素.
- 了解效应物如何从内分体中释放到它们的亚细胞点.
主要方法:
- 研究病原体分泌系统与宿主内细胞分裂之间的联系.
- 分析宿主细胞反应和参与CME的信号通路.
- 追踪效应蛋白在内体内和最终目的地内的运动.
主要成果:
- 这项研究提供了关于病原体分泌途径如何通过CME通过效应因子内部化影响的见解.
- 确定引发CME的特定宿主细胞因子和病原体分子.
- 阐明了从内分泌体释放因子和随后的亚细胞局部化的机制.
结论:
- 病原体作用者利用CME进入植物细胞,分泌途径在这个过程中发挥作用.
- 了解CME触发物和效应物释放机制对于开发新型植物疾病控制策略至关重要.
更多相关视频
11:50Bacterial Leaf Infiltration Assay for Fine Characterization of Plant Defense Responses using the Arabidopsis thaliana-Pseudomonas syringae Pathosystem
Published on: October 1, 2015
08:45Assay for Pathogen-Associated Molecular Pattern PAMP-Triggered Immunity PTI in Plants
Published on: September 9, 2009
相关概念视频
Receptor-mediated Endocytosis
Intracellular Movement of Viruses and Bacteria
Mechanism of Filopodia Formation
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
Defenses Against Pathogens and Herbivores
Plasmodesmata
Endocytosis
Endocytosis always begins with the plasma membrane enclosing an incoming molecule to form a transport vesicle which, in some cases, can be coated with a protein called ‘clathrin.' Endocytosed material is either...
