在重症监护室的COVID-19相关的细菌感染:一个病例对照研究
Bahar Kaçmaz1, Şiran Keske2,3, Uluman Sişman4
1Department of Infectious Diseases and Clinical Microbiology, American Hospital, Istanbul, Turkey.
Scientific reports
|August 16, 2023
概括
与非COVID-19患者相比,COVID-19患者的二次细菌感染 (SBI) 显著增加,特别是阳性细菌. COVID-19,输管时间和男性性别预测SBI,而COVID-19也预测死亡率.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 细菌学 细菌学是一门学科.
背景情况:
- 二次性细菌感染 (SBI) 是重症患者的一个重大问题.
- 了解COVID-19患者SBI的发生率和预测因素对于改善结果至关重要.
研究的目的:
- 为了比较SBI在重症监护室 (ICU) 患有和没有COVID-19的患者的发病率.
- 为了确定SBI和COVID-19患者死亡率的预测因素.
主要方法:
- 从2020年1月到2022年4月进行的回顾性病例控制研究.
- 包括405名成年ICU患者,其中135人被诊断为COVID-19.
- 分析了人口统计数据,停留时间,输管日和细菌感染类型.
主要成果:
- 在COVID-19患者中,SBI的发病率更高 (34%对10.7%) 和高阳性肺炎的发病率更高.
- 预测SBI的预测因素包括COVID-19诊断,更长的输管时间和男性性别.
- COVID-19,输管时间,血液恶性瘤,固体瘤和冠状动脉疾病预测死亡率.
结论:
- COVID-19是ICU患者中二次细菌感染和死亡率的独立预测因素.
- 针对SBI的有针对性的监测和管理策略在COVID-19患者中是有必要的.
- 对甲基西林敏感的金黄色葡萄球菌是最常见的SBI;在COVID-19患者中没有检测到耐卡巴胺的肠杆菌.
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