乳酸菌种群基因组学Lacticaseibacillus paracasei:泛基因组,综合性prophage,抗生素耐药性和碳水化合物利用率
Zhangming Pei1,2, Xiaoshu Li1,2, Shumao Cui1,2
1State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.
World journal of microbiology & biotechnology
|August 16, 2023
概括
基因组分析揭示了Lacticaseibacillus paracasei的种群结构,生态和抗生素耐药性. 这项研究有助于识别功能性食品的有益益生菌株,并确保发酵期间的安全性.
科学领域:
- 微生物学 微生物学
- 基因组学就是基因组学.
- 食品科学 食品科学 食品科学
背景情况:
- 乳酸菌 (Lacticaseibacillus paracasei) 是一种具有健康益处的益生菌,特别是在乳制品中.
- 了解其种群结构,生态和抗生素耐药性对于其应用至关重要.
- 最近的重新分类增加了对这种物种的研究兴趣.
研究的目的:
- 通过基因组方法调查Lacticaseibacillus paracasei的种群结构,生态,进化和多样性.
- 分析Lc.中的抗生素耐药性和碳水化合物利用率. 一个假象的例子.
- 为了评估安全性评估,评估prophage诱导性和抗生素耐受性.
主要方法:
- 基因组分析了121个自我隔离的和268个公共的Lc. 帕拉凯西基因组.
- 在孤立菌株中评估综合的prophage诱导性.
- 抗生素耐药性表型的确定.
主要成果:
- 基因组数据提供了对Lc.c.的见解. 类别分类学,生态学,进化和多样性.
- 阐明了整合的先导相关元素的分布和抗生素耐药性模式.
- 孤立的菌株对多种抗生素表现出耐受性,并评估了prophage诱导性.
结论:
- 基因组洞察力增强对Lc的理解. 适用于益生菌的应用.
- 该研究提供了对Lc.安全性评估的数据. 在食品发酵中的Paracasei.
- 对Lc进行进一步的研究. 帕拉凯西可以优化有益菌株的选择.
关键词:
抗生素耐药性 抗生素耐药性碳水化合物的利用率进行比较的基因组学.乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶 乳糖酶泛基因组是一个全基因组.原体的前体细胞是什么更多相关视频
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