相关实验视频

Updated: Jul 19, 2025

Identification of Circular RNAs using RNA Sequencing

Identification of Circular RNAs using RNA Sequencing

Published on: November 14, 2019

全球循环RNA研究的图书统计分析:现状和未来方向

Lv Yehui^1,2, Li Zhihong^1,2, Tong Fang^2,3

¹Institute of Wound Prevention and Treatment, Shanghai University of Medicine and Health Sciences, Shanghai, China.

Molecular biotechnology

|August 16, 2023

概括

自2015年以来,循环RNA (circRNAs) 的全球研究迅速扩大,出版物和引用的数量大幅增加. 未来的研究很可能会关注circRNAs在癌症和其他疾病中的诊断和治疗潜力.

科学领域:

分子生物学分子生物学
基因组学就是基因组学.
生物信息学是一种生物信息学.

背景情况:

循环RNAs (circRNAs) 是一种新型的RNA分子类别,引起了越来越多的研究兴趣.
它们独特的结构和调控功能,特别是作为微RNA (miRNA) 海绵,是研究的关键领域.

研究的目的:

对2010年至2022年全球circRNA研究进行文献计量分析.
确定circRNAs领域的当前趋势,关键参与者和未来研究方向.

主要方法:

从科学网络核心集合中检索数据,使用circRNA相关术语.
使用CiteSpace软件计算和可视化的图书统计指标.
分析出版物输出,引用数量,顶级出版国家和突出的circRNAs.

主要成果:

总共有7,385个circRNA研究被确定,在2015年之后,输出和引用的显著增加.
中国,美国和德国是circRNA研究的领先国家.
最受研究的circRNAs (circCDR1as,circHIPK3,circPVT1,circSHPRH,circZNF609) 主要与癌症有关.
研究重点已经从转录循环化和miRNA海绵化等基本机制转移到转录学,瘤抑制和生物标志物开发等应用领域.

结论:

循环RNA研究是一个快速发展和高度活跃的领域,有明显的应用研究趋势.
未来的研究预计将探索circRNAs在瘤学和其他疾病中的诊断和治疗应用.
需要进一步研究 circRNAs 在各种病理状况中的机制和功能.

关键词:

图书统计学分析在CiteSpace中使用CiteSpace.当前状态当前状态当前状态未来的方向未来的方向环绕RNAss 的时间.

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In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

Published on: October 21, 2022

Use of Alu Element Containing Minigenes to Analyze Circular RNAs

Use of Alu Element Containing Minigenes to Analyze Circular RNAs

Published on: March 10, 2020

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