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Updated: Jul 19, 2025

Measuring Single-Cell Mitochondrial DNA Copy Number and Heteroplasmy Using Digital Droplet Polymerase Chain Reaction
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Published on: July 12, 2022

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人类mtDNA复制数和异质体的核遗传控制

Rahul Gupta1,2,3, Masahiro Kanai4,5, Timothy J Durham6,4

  • 1Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA. rahul_gupta@hms.harvard.edu.

Nature
|August 16, 2023
PubMed
概括

核基因组变异影响线粒体DNA (mtDNA) 拷贝数和异质体. 这项研究揭示了对mtDNA丰富性和遗传性的遗传控制,影响了人类的健康和衰老.

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