原发性皮肤冠状动脉干预在患有自发性冠状动脉剖析与冠状动脉疾病的患者中
Fernando Alfonso1, Cristina Fernández-Pérez2, Náyade Del Prado3
1Department of Cardiology, Hospital Universitario de La Princesa, Universidad Autónoma de Madrid, IIS-IP, CIBER-CV, Madrid, Spain.
JACC. Cardiovascular interventions
|August 17, 2023
概括
主要穿皮冠状动脉干预 (PPCI) 用于自发冠状动脉剖析 (SCAD) 与ST段升高心肌梗塞 (STEMI) 显示与非SCAD STEMI相似的结果. 这支持PPCI.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 急性心肌梗塞急性心肌梗塞
背景情况:
- 自发冠状动脉解剖 (SCAD) 是急性心肌梗塞 (AMI) 的罕见原因.
- 在SCAD中重血管是具有挑战性的,最初不建议在没有高风险特征的稳定SCAD中进行.
研究的目的:
- 为了比较住院死亡率和30天再入院率.
- 评估SCAD患者的初级穿皮冠状动脉干预 (PPCI) 的结果,SCAD患者的ST段升高心肌梗塞 (STEMI) 与非SCAD STEMI患者相比.
主要方法:
- 该研究使用了西班牙国家卫生系统 (2016-2020) 的行政数据集.
- 计算了风险标准化的住院死亡率和再接收率.
- 倾向性得分 (PS) 分析经过调整以考虑混因素.
主要成果:
- 确定了65,957次PPCI事件;315 (0.5%) 是SCAD.
- SCAD PPCI患者年轻,主要是女性.
- 在SCAD PPCI和非SCAD PPCI组之间,即使在PS调整后,住院死亡率 (5.7%对比4.8%) 和30天再入院率 (3%对比4%) 也相似.
结论:
- 在SCAD的精选STEMI患者中,PPCI表明可比的住院死亡率和30天再入院率与动脉血性STEMI相似.
- 这些发现支持PPCI在特定SCAD情况下的实用性.
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