血管综合征和麻醉:一个叙事审查
Begüm Nemika Gökdemir1, Nedim Çekmen1
1Department of Anaesthesiology and Reanimation, Başkent University Faculty of Medicine, Ankara, Turkey.
Turkish journal of anaesthesiology and reanimation
|August 17, 2023
概括
血管综合征 (VAS) 是一种复杂的疾病,导致抗性低血压. 本综述详细介绍了VS诊断,病理生理学和麻醉管理,提供治疗算法以改善患者的治疗结果.
科学领域:
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
- 心血管外科心血管外科
背景情况:
- 血管综合征 (VS) 呈现为耐性低血压,尽管血管压缩剂和体积复苏.
- 这是大手术,创伤和败血症中常见的并发症.
- 病理生理学涉及血管光滑肌肉细胞介导体的不平衡.
研究的目的:
- 审查VS的诊断和诱导因素.
- 阐明VS的复杂病理生理学.
- 概述VS的治疗策略和麻醉管理.
主要方法:
- 关于血管综合征的综合文献综述.
- 诊断标准和病理生理机制的分析.
- 评估当前和新兴的治疗方式.
主要成果:
- VS病变包括iNO的过度产生,K+通道刺激,NF-κB激活和V1A受体下调.
- 治疗选择包括体积,内类药物,血管压素,甲基蓝,以及其他如血管激素II.
- 尽管取得了进展,但死亡率仍然很高,为30-50%.
结论:
- 对于麻醉科医生来说,有效诊断和管理VS是具有挑战性的.
- 提出了一个结构化的治疗算法来指导临床实践.
- 需要进一步的研究来改善VS患者的治疗结果.
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