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Updated: Jul 19, 2025

An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity
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在tRNA修饰中选择性甲基化5-碳素甲基尤里丁的结构基础

Jaehun Yoo1, Jangmin Lee1, Jungwook Kim1

  • 1Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.

Nucleic acids research
|August 17, 2023
PubMed
概括

细菌tRNA的修饰涉及到由CmoM甲基化的5-carboxymethoxyuridine. 晶体结构揭示了CmoM如何识别特定的tRNA特征,例如34位的5-carboxymethoxyuridine,以获得准确的甲基化.

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