在10年的时间里 (2012-2021) 在14个马类实践中使用抗生素
Rose E Tallon1, Brian Whitt2, Bruce M Bladon1
1Donnington Grove Veterinary Group, Berkshire, UK.
Equine veterinary journal
|August 17, 2023
概括
这项研究提供了一种可靠的方法来监测十年来英国兽医实践中马类抗生素的使用情况. 这些发现为抗微生物药物管理审计提供了基线,强调了动物每日定义剂量的有用性 (DDDvet).
科学领域:
- 兽医药理学 兽医药理学
- 抗微生物耐药性 抗微生物耐药性
- 马的健康 马的健康
背景情况:
- 监测抗生素的使用对于打击兽医中的抗菌素耐药性至关重要.
- 之前的研究已经描述了用于马类抗生素监测的计算机记录使用,但报告指标缺乏共识.
- 这项研究解决了在马类抗菌素使用监测中需要标准化指标的需求.
研究的目的:
- 在10年的时间里 (2012-2021) 记录英国马类实践中的抗生素使用情况.
- 使用商用实践管理软件进行数据收集和分析.
- 建立一个可靠的方法来测量和报告马类抗生素消耗.
主要方法:
- 采用了追溯调查设计.
- 通过使用Eclipse®实践管理软件从14个马术实践中收集数据.
- 报告的抗生素销售量是mg/kg,并使用动物定义的每日剂量 (DDDvet) 和DDD/1000只动物进行校正,以考虑剂量变化.
主要成果:
- 在14个实验室 (治疗多达107977匹马) 中,年平均抗生素使用量为54.25毫克/公斤.
- 计算的使用指标包括1.52 DDDvet/动物/年和4.17 DDD/1000动物.
- 最优先级的临界重要抗微生物药物的中位数使用量为0.67 mg/kg,0.12 DDDvet/动物/年,0.33 DDD/1000 个动物.
结论:
- 成功实施了一种可靠的测量马类抗生素使用的技术.
- 动物定义的每日剂量 (DDDvet) 度量在马类实践中特别有用,因为常用的是增强型硫胺.
- 提出的数据和方法可以为未来的临床审计奠定基础,以改善马匹实践中的抗菌药物管理.
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