乳腺癌患者高强度间歇训练:系统性审查和元分析
Xudong Chen1,2, Xuyuan Shi1,2, Zhiruo Yu1,2
1Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Cancer medicine
|August 17, 2023
概括
高强度间歇训练 (HIIT) 与通常护理相比,在乳腺癌幸存者中显著改善心肺健康. 这种运动干预也可以增强肌肉力量,减少疲劳和情绪困扰.
科学领域:
- 在瘤学瘤学.
- 运动生理学 运动生理学
- 康复医学 康复医学 康复医学
背景情况:
- 乳腺癌幸存者经常面临与治疗相关的损害,影响生活质量.
- 高强度间歇训练 (HIIT) 显示出作为癌症患者的运动疗法的潜力.
- 目前关于HIIT对乳腺癌患者的影响的研究是有限和矛盾的.
研究的目的:
- 系统地审查和元分析HIIT对乳腺癌患者健康相关结果的影响.
- 将HIIT与通常护理 (UC) 和中等强度持续训练 (MICT) 进行比较.
- 评估对身体健康,身体组成,生物标志物和患者报告结果的影响.
主要方法:
- 在PubMed,Embase和Web of Science数据库进行系统搜索,截至2022年11月.
- 包括随机对照试验,比较乳腺癌患者的HIIT与UC或MICT.
- 身体健康 (VO2峰值),身体成分和生物标志物的元分析;对其他结果进行系统审查.
主要成果:
- 包括10项研究,532名参与者.
- 与UC相比,HIIT显著改善了峰值氧气吸收 (VO2峰值) (L/min的SMD为0.79,mL/kg/min的SMD为0.59).
- 在HIIT和MICT之间,VO2峰值没有显著差异;身体成分或生物标志物与UC没有显著变化. 观察到对肌肉力量,疲劳和情绪健康的有利影响.
结论:
- HIIT是一种节省时间的运动方式,用于改善乳腺癌患者的心肺呼吸能力.
- HIIT也可能对肌肉力量,疲劳和情绪健康产生积极影响.
- 在乳腺癌治疗的运动处方中应该考虑HIIT,需要进一步研究其他结果的临床意义.
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