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Updated: Jul 19, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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综合性后基因组广泛关联研究分析与精神疾病相关:推算转录组和蛋白质组信号

Huseyin Gedik1, Roseann E Peterson2, Brien P Riley2

  • 1Integrative Life Sciences, Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.

Complex psychiatry
|August 17, 2023
PubMed
概括

全基因组关联研究 (GWAS) 确定复杂特征的遗传变异. 全转录组关联研究 (TWAS) 和全蛋白组关联研究 (PWAS) 通过将基因表达和蛋白质水平与特征联系起来来扩展这一点,有助于精神疾病研究.

关键词:
表达方式 定量特征位置.蛋白质的定量特征位置.全蛋白质组协会研究研究.精神病学是一个精神病学.转录组范围的关联研究研究.

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A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior06:59

A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior

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