通过平面超声波阵列进行3D原声学成像:模拟工作流程
Pratik Samant1, Luis M Trevisi2, Yong Chen3
1Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, 73071, USA and now is with the Department of Oncology, University of Oxford, and Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordshire, UK.
IEEE transactions on radiation and plasma medical sciences
|August 17, 2023
概括
质子疗法现在可以使用脉冲质子束的声波来创建3D图像,提高精度. 这种原声学成像技术即使有大量的背景噪声也能工作.
科学领域:
- 医学物理 医学物理
- 声学成像 声学成像
- 辐射瘤学 辐射瘤学
背景情况:
- 质子疗法面临的挑战是布拉格峰值范围的不确定性,影响治疗的精度.
- 脉冲的质子束产生原声辐射,与吸收的能量相关,并包含剂量计信息.
研究的目的:
- 使用超声波阵列推导和建模3D原声学成像.
- 为了研究原声学辐射的频率特征.
- 评估在噪音条件下图像重建的可行性.
主要方法:
- 开发一种形式主义来表征原声信号,考虑到传感器带宽和质子束脉冲持续时间.
- 从Mevion S250临床机器获得实验性质子束强度数据.
- 使用超声波阵列从声波排放中进行3D图像重建.
主要成果:
- 证明了3D原声学图像重建的可能性,即使噪声超过信号幅度.
- 基于光束属性和传感器规格的原声学信号的特征.
- 确定MHz范围信号可以由具有足够温度梯度的4μs高斯质子脉冲产生.
结论:
- 原声学成像为质子疗法中剂量测量和3D成像提供了一种新的方法.
- 开发的形式主义为理解和优化原声信号检测提供了一个框架.
- 该技术在临床相关场景中显示出可靠的图像重建的前景.
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