具有P53异常的B细胞前淋巴细胞白血病成功地用bendamustine和rituximab治疗:报告了三个病例
Anna Wang1, Wei Guo1, Daniela Damiani2
1Department of Hematology, Tumor Center, The First Hospital of Jilin University, Changchun, China.
Translational cancer research
|August 17, 2023
概括
班达穆斯丁和修复药 (BR) 化疗对治疗B细胞前淋巴细胞白血病 (B-PLL) 有前途. 这种疗法在3名具有侵略性B-PLL的患者中实现了深度缓解,包括那些P53异常患者.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 临床医学 临床医学
背景情况:
- B细胞前淋巴细胞性白血病 (B-PLL) 是一种罕见的,具有攻击性的成熟B细胞瘤,预后不佳.
- 标准的第一线治疗包括基于纯素模拟的化疗免疫疗法.
- 由于B-PLL的罕见性,对Bendamustine和Rituximab (BR) 疗法的疗效存在有限的数据.
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