肩部手术前抗菌洗对Cutibacterium的有效性:系统性审查和元分析
Andrew P Collins1, Jeffrey Simpson1, Bradley Richey1
1Orlando Health Jewett Orthopedic Institute, Orlando, FL, USA.
JSES reviews, reports, and techniques
|August 17, 2023
概括
在肩膀手术前,氧化 (BPO) 在减少Cutibacterium方面比氧化 (CHG) 更有效. BPO提供了一种简单,经济的选择,可以降低细菌负担并改善外科手术结果.
科学领域:
- 整形外科 整形外科 整形外科
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
背景情况:
- 菌 (C. acnes) 在修复肩膀关节整形术中很常见.
- 标准素酸盐 (CHG) 对皮肤C. acnes的有效性有限.
- 过氧化 (BPO) 在根除C. acnes方面表现有前途.
研究的目的:
- 比较使用CHG与BPO在家肩部脱殖的疗效.
- 在肩膀手术前评估减少C. acnes负担.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在PubMed和MEDLINE上搜索了关于肩膀C. acnes的CHG和BPO研究.
- 使用随机效应模型,从随机对照试验 (RCT) 和非RCT中汇集数据.
主要成果:
- 与RCT和非RCT中的对照相比,BPO和CHG都显著降低了C. acnes培养的阳性.
- 与CHG相比,BPO在RCT中显示出C. acnes培养阳性的统计学上显著更大降低.
- 方法质量评估显示,大多数研究具有偏差风险低至中等.
结论:
- 手术前的CHG和BPO有效地减少了肩膀C..
- BPO似乎比CHG更有效,可能是由于皮肤透率更好.
- BPO提出了一种简单,具有成本效益的药物,用于减少肩膀手术患者的C. acnes.
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