关于目前和未来韩国对异尼抗单抗结核病的指导方针的德尔菲调查
Wan Seo1, Hyung Woo Kim2, Eung Gu Lee3
1Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Infection and drug resistance
|August 17, 2023
概括
需要更新的指导方针,对单一抗异化结核病 (Hr-TB) 的治疗. 专家建议进行分子药物敏感性测试,并进行为期六个月的治疗方案,并根据pyrazinamide的使用情况进行调整.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 异尼胺单抗结核病 (Hr-TB) 是一个重大的全球卫生挑战.
- 现有的Hr-TB诊断和治疗指南需要巩固和专家达成共识.
研究的目的:
- 巩固韩国关于对异化单抗结核病 (Hr-TB) 管理的指导方针.
- 收集专家意见并就HR-TB诊断和治疗策略达成共识.
主要方法:
- 在韩国,对96名结核病专家进行了两轮的Delphi调查.
- 该调查涵盖了关于Hr-TB的诊断,治疗和一般意见.
主要成果:
- 在96名专家中,有72名专家参加了会议.
- 96%的人同意分子药物敏感性测试 (DST) 来检测异化和利法的耐药性.
- 超过95.8%的人推六个月的治疗方案 (利法,乙醇,皮拉津胺,勒沃素),对皮拉津胺的持续时间进行修改.
结论:
- 德尔菲调查成功实现了韩国关于Hr-TB诊断和治疗的专家共识.
- 这些发现将为韩国对Hr-TB管理的修订指南提供信息.
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