在高海拔地区生活的适应气候低地人群中,高动脉氧和度很高
Yaoxi He1, Chaoying Cui2, Yongbo Guo1
1State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223 China.
Phenomics (Cham, Switzerland)
|August 17, 2023
概括
高海拔生活会影响血液中氧和度 (SpO2). 与预期相反,汉族华人移民的SPO2比藏族本土人高,但慢性山病率也更高,这表明单独的SPO2不是可靠的绩效指标.
科学领域:
- 生理学 生理学 生理学
- 高度医学 高度医学
- 人类的适应能力
背景情况:
- 血液中氧和度 (SpO2) 对于评估氧气水平至关重要.
- 在高海拔地区的低SPO2与低氧症的疾病和死亡有关.
- 之前关于移民在高海拔地区的SpO2水平的假设缺乏经验数据.
研究的目的:
- 为了在高海拔地区比较藏族原住民和汉族华人移民之间的动脉氧和度.
- 调查SpO2,高度和慢性山病患病率之间的关系.
- 确定SPO2是否是高海拔群体生理性能的可靠指标.
主要方法:
- 涉及5929名藏族本土人和1034名汉族华人移民的比较研究.
- 从1120米到5020米的高度收集数据.
- 对动脉氧和和慢性山病的流行率的分析.
主要成果:
- 汉族中国移民在同等高海拔地区的SPO2比藏族本地人高.
- 与藏人相比,汉族移民的慢性山病患病率更高.
- 适应气候的汉族中较高的SpO2与生理成本有关,而藏族的SpO2似乎不够理想.
结论:
- 高海拔居民的SpO2水平复杂且取决于人口.
- 在高海拔地区的汉族移民中,较高的SpO2与慢性山病的风险增加有关.
- 单独的SpO2不是评估高海拔地区生理性能的足够指标.
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