在选择性穿皮冠状动脉干预中控制压力间歇性冠状动脉鼻封闭的成本效益分析
Carla Rognoni1, Gaia Segantin1, Roberto Scarsini2
1Centre for Research on Health and Social Care Management (CERGAS), SDA Bocconi School of Management, Bocconi University, Milan, Italy.
Expert review of pharmacoeconomics & outcomes research
|August 17, 2023
概括
通过压力控制的间歇性冠状动脉鼻封闭 (PCI+PiCSO) 的皮肤冠状动脉干预是一种成本有效的治疗ST升高的心肌梗塞. 这种创新方法改善了患者的治疗结果和生活质量,与单独使用标准的PCI相比.
科学领域:
- 心脏病学 心脏病学
- 卫生经济学 卫生经济学
背景情况:
- 穿皮冠状动脉干预 (PCI) 是ST升高心肌梗塞的标准,但有频繁的死亡率和心力衰竭.
- 压力控制的间歇性冠状动脉鼻闭塞 (PiCSO) 可以减少心脏病发作的大小并改善患者的治疗结果.
研究的目的:
- 从意大利国家医疗服务 (NHS) 的角度来评估PCI加PiCSO与PCI单独相比的成本效益.
- 评估PCI+PiCSO对寿命年 (LY) 和质量调整寿命年 (QALY) 的影响.
主要方法:
- 开发了一个马尔科夫模型来估计LY,QALY和成本.
- 微成本分析确定了PCI+PiCSO程序的成本.
- 进行了灵敏度分析,以确保模型的稳定性.
主要成果:
- 在PCI+PiCSO中,ICUR为17.530欧元/QALY,ICER为14.631欧元/LY,这表明了成本效益.
- 在78.8%的模拟中,该策略被发现具有成本效益.
- 如果程序成本低于28,160.0欧元,那么PCI+PiCSO是具有成本效益的.
结论:
- PCI+PiCSO是一种潜在的具有成本效益的技术,用于管理ST升高心肌梗塞.
- 该程序可以减少心脏事件,并提高患者的预期寿命和生活质量.
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