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Updated: Jul 19, 2025

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
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黄素与有机离子载体3的抑制相互作用及其结构-活性关系用于预测脏保护作用

Feng-He Wang1, Hui-Xin Tan1, Jia-Huan Hu1,2

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

Journal of Asian natural products research
|August 17, 2023
PubMed
概括

这项研究确定了有机离子载体3 (OAT3) 的五种强有力的黄类抑制剂. 这些黄类化合物减少OAT3介导的急性损伤 (AKI),并为药物开发提供了洞察力.

关键词:
在OAT3中使用OAT3.急性脏损伤急性脏损伤是什么黄类化合物 黄类化合物抑制抑制抑制的抑制作用结构 - 活动关系结构 - 活动关系

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