招募手术和术后随机对照试验的方法:快速审查
Maya Morton Ninomiya1, Jenna Hiemstra1, Emma Nicholson2
1Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.
World journal of surgery
|August 17, 2023
概括
招募参与者进行手术随机对照试验 (RCT) 是困难的. 成功的试点RCT使用了代评估和分阶段引入,但患者的意见缺少.
科学领域:
- 临床试验 临床试验
- 手术研究的研究.
- 方法论 方法论 方法论
背景情况:
- 手术随机对照试验 (RCT) 面临着重大招聘挑战.
- 试点研究对于评估可行性和优化招聘策略至关重要.
研究的目的:
- 确定成功的试点手术和外科手术期间的RCT的特征.
- 报告优化招聘的方法策略.
- 为未来的外科RCT招聘提供建议.
主要方法:
- 系统的文献搜索欧维德的MEDLINE,EMBASE和科学网络 (2012-2022年).
- 包括符合招聘目标的试点外科和外科外科实验室.
- 研究/招聘特征的总结和招聘策略的评估.
主要成果:
- 包括52项试点研究;21%缺乏明确的招聘目标.
- 招聘优化策略包括代评估和分阶段的研究引入.
- 招募率与干预的侵入性或参与负担无关.
结论:
- 通过代的定性评估,可以加强手术RCT的招聘.
- 纳入跨学科团队投入和患者参与对于优化招聘至关重要.
- 目前关于试点研究中招聘方法的报告不足.
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