后膜炎的挑战 - 视网膜专家的技巧和技巧
Manuel Paez-Escamilla1, Sonny Caplash1, Gagan Kalra1
1Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Journal of ophthalmic inflammation and infection
|August 17, 2023
概括
后膜炎可以模仿其他视网膜疾病,造成诊断挑战. 这篇综述强调了罕见的脑膜炎表现和伪装者,强调多式成像用于准确的诊断.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 管道炎管理 管道炎管理
背景情况:
- 后膜炎是一种常见的胆管关节疾病,原因多种多样,包括传染病和自身免疫性疾病.
- 新生病状况可以模仿后膜炎,称为"伪装者",使诊断和治疗复杂化.
- 区分罕见的后部紫外线和伪装者是一个诊断困境,往往导致延迟治疗.
研究的目的:
- 总结后部紫外线与罕见的发现.
- 审查那些难以区分于脑膜炎的伪装综合征.
- 为诊断具有挑战性的后膜实体提供一个概要.
主要方法:
- 在MEDLINE/PUBMED,EBSCO和Cochrane CENTRAL数据库中进行了广泛的文献搜索.
- 包括1985年1月至2022年1月的原始研究和评论.
- 专注于预先确定的诊断,包括后部脑膜炎实体,脑膜炎和伪装综合征.
主要成果:
- 模仿后膜炎的疾病包括免疫检查点抑制剂和Vogt-Koyanagi-Harada类膜炎,白血病和淋巴瘤.
- 模仿视网膜疾病的炎症性疾病包括系统性红斑狼的普尔切尔类视网膜病变和中央血清性胆网膜病变.
- 罕见的脑膜炎病因包括矛盾的抗TNF-α效应,接种疫苗后的脑膜炎,以及眼睛炎症后的肠膜抗血管药物.
结论:
- 后膜炎与Purtscher-like视网膜病变和矛盾的抗TNF-α效应等疾病具有重叠的特征.
- 视网膜疾病,如缺血眼综合征,中枢视网膜静脉封闭和遗传性疾病,可以模仿脑膜炎.
- 准确的诊断需要审查患者病史,药物,疫苗,并利用多式联网膜成像和遗传检测.
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