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二氧化碳吸入可减少结肠镜检查后性结肠炎的复发:一项随机对照试验
Yuriko Otake-Kasamoto1, Shinichiro Shinzaki1,2, Satoshi Hiyama1
1Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
PloS one
|August 17, 2023
概括
结肠镜检查期间的二氧化碳 (CO2) 输入可以减少性结肠炎患者的腹部不适. 它还降低了未完全缓解的患者的8周临床复发率,改善了结肠镜检查结果.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 炎症性肠道疾病是什么
背景情况:
- 结肠镜对于性结肠炎 (UC) 管理至关重要,但可以引发疾病爆发.
- 二氧化碳 (CO2) 吸入可减少结肠镜后的不适,但其对UC恶化的影响尚不清楚.
研究的目的:
- 评估在结肠镜检查期间CO2灌注对性结肠炎患者疾病恶化的影响.
主要方法:
- 96名正在缓解的UC患者在结肠镜检查期间被随机分配到CO2或空气灌气中.
- 评估了手术后的腹部不适和8周内临床复发率.
主要成果:
- 在手术后立即和30分钟内,CO2灌气显著减少了腹痛和腹.
- 整体临床复发没有差异,但CO2组在没有完全缓解的患者中显示出较低的8周复发.
结论:
- 在接受结肠镜检查的UC患者中,CO2 insufflation可以缓解腹部不适.
- 在UC患者中,CO2可能会降低UC患者在8周后的临床复发率,而UC患者无法实现完全缓解.
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