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通过调节AMPK-mTOR-TFEB轴,NCoR1控制了髓状细胞中Mycobacterium结核病的生长

Viplov Kumar Biswas1,2, Kaushik Sen1,3, Abdul Ahad1

  • 1Immuno-genomics & Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, India.

PLoS biology
|August 17, 2023
PubMed
概括

核受体核心压缩剂1 (NCoR1) 是一个关键的宿主因子,控制了髓状细胞中Mycobacterium tuberculosis (Mtb) 的生长. NCoR1调节了自和溶酶体生物发生,影响了Mtb的病变发生.

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