补充氧疗法在间歇性肺部疾病:一个叙事审查
Kristopher P Clark1,2, Howard B Degenholtz3, Kathleen O Lindell4,5
1Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Pittsburgh-UPMC.
Annals of the American Thoracic Society
|August 17, 2023
概括
补充氧气通常用于间歇性肺病 (ILD),但其益处的证据有限. 由于未知结果和潜在障碍,建议采用以患者为中心的方法.
科学领域:
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
- 临床结果研究研究
背景情况:
- 患有间歇性肺部疾病 (ILD) 的患者经常出现低氧症,需要补充氧气治疗.
- 估计40%的ILD患者可能需要补充氧气,许多人需要高流量支持 (>4L/分钟).
- 目前在ILD中使用氧气的建议主要基于慢性阻塞性肺病 (COPD) 的研究,在ILD中具体证据有限.
研究的目的:
- 审查有关补充氧气对ILD患者临床结果的影响的现有证据.
- 突出有关ILD氧气使用的知识差距,包括患者报告的结果和成本效益.
- 为临床实践提供有关在ILD中补充氧的处方的信息,考虑潜在的益处和负担.
主要方法:
- 关于在ILD中使用补充氧气的现有研究的文献评论.
- 分析当前的临床指南及其对ILD的适用性.
- 考虑患者报告的结果,成本和医疗保健政策影响.
主要成果:
- 现有证据表明,补充氧气可能会改善一些低氧症ILD患者的生活质量和运动参数.
- 然而,氧气治疗可能会带来负担和障碍,这些负担和障碍可能会抵消好处.
- 在ILD中氧气的成本是相当大的,并且退款政策可能会限制获得高流氧气服务的机会.
结论:
- 需要未来的研究来调查氧气使用的临床和生活质量结果,特别是在ILD患者中.
- 鉴于有限的证据,成本和潜在障碍,在为ILD处方补充氧时,以患者为中心的方法至关重要.
- 医疗服务提供者应仔细权衡潜在的好处与负担和成本对每位需要氧气治疗的ILD患者.
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