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Updated: Jul 14, 2026

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在人体体体内测量脂肪组织动力学,使用 (2H) 标记方法

Dereck Kibodeaux1, Jonathan Savoie1, Eric Ravussin1

  • 1Pennington Biomedical Research Center, Louisiana State University System.

Journal of visualized experiments : JoVE
|August 17, 2023
PubMed
概括

研究人员开发了一种新的方法,使用带标记的水来测量人类脂肪组织细胞周转率. 这种创新技术在体内准确量化脂肪细胞的形成和死亡,进步了我们对代谢健康的理解.

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Measurement of Bioavailability: Pharmacodynamic Methods

Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.