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针对非洲天然产品进行集体式虚拟选,以准人体甲基酸合成酶

Denis Mteremko1, Jaffu Chilongola2, Andrew S Paluch3

  • 1The Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania.

Journal of molecular graphics & modelling
|August 17, 2023
PubMed
概括

研究人员确定了强大的抗癌化合物NEA4433和NEA4434,向人体甲基酸合成酶 (hTS). 这些天然化合物具有很高的结合亲和力和稳定的相互作用,突出显示了水在hTS的药物发现中的作用.

关键词:
非洲天然产品 非洲天然产品癌症治疗方法 癌症治疗方法整体对接的对接方式人类甲基甲基甲酸合成酶放松复杂的计划 放松复杂的计划虚拟选是一个虚拟的选.

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